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Whether you’re battling a cold, managing pain or treating a chronic condition, prescription and over-the-counter medicine costs can add up. But the right card could reward you for pharmaceutical purchases to cover future copays or put extra cash in your wallet.

Here are our picks for cards to swipe next time you’re at the pharmacy or drugstore checkout.

Top cards for pharmacies and drugstores

Best for U.S. supermarket pharmacies

Blue Cash Preferred® Card from American Express

Cardholder rating

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4.3

Bankrate score

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4.4

Bankrate review

Bankrate review

Recommended credit score:Good to Excellent

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on American Express‘s secure site

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$0 intro annual fee for the first year, then $95.

Best for drugstores

Chase Freedom Unlimited®

Cardholder rating

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4.3

Bankrate score

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5.0

Bankrate review

Bankrate review

Recommended credit score:670 – 850

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on Chase‘s secure site

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18.99% – 28.49% Variable

Best for rotating rewards

Discover it® Cash Back

Cardholder rating

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4.4

Bankrate score

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4.1

Bankrate review

Bankrate review

Recommended credit score:670 – 850

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on Discover‘s secure site

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18.24% – 27.24% Variable APR

Best for customizable rewards

Bank of America® Customized Cash Rewards credit card

Cardholder rating

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4.4

Bankrate score

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3.8

Bankrate review

Bankrate review

Recommended credit score:670 – 850

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on Bank of America‘s secure site

18.24% – 28.24% Variable APR on purchases and balance transfers

Get a $150 Amazon Gift Card

19.49% – 28.24% Variable

Best for Walgreens

Bilt Mastercard®

Cardholder rating

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4.1

Bankrate score

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4.0

Bankrate review

Bankrate review

Recommended credit score:670 – 850

Apply nowLock

on Bilt‘s secure site

See Rates & Fees

compare

Comparing the best cards for pharmacies and drugstores

Card name Best for Annual fee Recommended credit score Rewards
Blue Cash Preferred® Card from American Express U.S. supermarket pharmacies $0 intro annual fee for the first year, then $95. Good to Excellent (670 – 850)
  • 6% cash back at U.S. supermarkets (on up to $6,000 in purchases per year, then 1%)
  • 6% on select U.S. streaming services
  • 3% on transit and U.S. gas station purchases
  • 1% on all other purchases
Chase Freedom Unlimited® Drugstores $0 Good to Excellent (670 – 850)
  • 5% cash back at Chase Travel
  • 3% on drugstore purchases and dining
  • 1.5% on all other purchases
Discover it® Cash Back Rotating rewards $0 Good to Excellent (670 – 850)
  • 5% cash back on activated rotating categories each quarter (up to $1,500 in purchases, then 1%)
  • 1% on all other purchases
Bank of America® Customized Cash Rewards credit card Customizable rewards
$0
Good to Excellent (670 – 850)
  • 3% cash back in one of six choice categories
  • 2% at grocery stores and wholesale clubs ($2,500 spending limit in combined quarterly purchases for 2% and 3% categories, then 1%)
  • 1% on all other purchases
Prime Visa Amazon Pharmacy and Whole Foods supplements $0 (Amazon Prime subscription required) Good to Excellent (670 – 850)
  • 5% cash back at Amazon.com, Amazon Fresh, Whole Foods Market and Chase Travel with an eligible Prime membership
  • 2% at gas stations, restaurants, and on local transit and commuting
  • 1% on all other purchases
Bilt Mastercard® Walgreens
$0
Good to Excellent (670 – 850)
  • 3X points on dining
  • 3X points on Lyft
  • 2X on travel
  • 2X on Walgreens products
  • 1X on rent (up to 100,000 points per calendar year)
  • 1X on all other purchases

Cards for pharmacies and drugstores typically require a good-to-excellent credit score. If you have bad or fair credit, consider our top picks for cards for bad credit.

How to choose a drugstore credit card

When choosing a credit card for drugstores, you’ll want to consider your medical needs, how often you visit pharmacies and where you do most of your shopping.

  • Consider whether you tend to fill prescriptions at drugstores or grocery store pharmacies. The cards above differ in which types of pharmacies earn a rewards rate. If you get prescriptions somewhere else that’s not typically rewarded, a flat-rate rewards card might be a better option.
  • Check for spending caps. Some cards limit how much quarterly spending you’ll get a high rate for, so it’s ideal if you can reach the spending cap without going too far over. If you do exceed the spending limit, you could switch to a higher flat-rate card for the remainder of the quarter.
  • Look at your other types of expenses. If your pharmaceutical spending is seasonal or you want to use the card for other categories too, compare the other rewards categories. Some of the cards above also reward spending on things like dining or streaming services.

How to maximize your pharmacy or drugstore rewards

While pharmacy or drugstore spending might seem like a narrow category, you can get the most possible cash back with these tips.

What’s next?

The bottom line

Which card you select for pharmacies and drugstores — or if you choose a different rewards card altogether — depends on your medical needs and everyday spending. You may or may not want to pay an annual fee to get even more bang for your buck. Swiping a different card for every expense can get tedious, so ideally, you could use one of the cards on this list to pay for pharmaceuticals as well as groceries, gas, dining or other everyday costs.

Frequently asked questions

The Bank of America® Customized Cash Rewards credit card information was last updated on June 9, 2025.

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